Insulin Resistance (HOMA-IR)
Computes HOMA-IR, QUICKI and glucose/insulin ratio from fasting glucose and insulin, compared to Turkish pediatric reference cutoffs (Kurtoğlu 2010). Screening only; not a diagnosis.
This tool is for information and screening only; it does not diagnose. Values must come from a fasting (≥8 h) blood sample. Cutoffs derive from an obese pediatric cohort and vary by lab/insulin assay. Diagnosis and management of insulin resistance are done by a clinician in clinical context.
Frequently asked questions
What is HOMA-IR?
HOMA-IR (fasting glucose × fasting insulin / 405) is a simple index estimating insulin resistance. Higher values suggest reduced insulin response. In children, cutoffs vary by age, puberty and sex; this tool uses Turkish reference cutoffs.
What do QUICKI and the glucose/insulin ratio add?
QUICKI is another measure of insulin sensitivity (higher = better). The fasting glucose/insulin ratio (FGIR) below 7 suggests insulin resistance in adolescents. Together they give a fuller picture.
How should values be obtained?
Both glucose and insulin must come from the same fasting (≥8 h) sample. Non-fasting values invalidate the result. Glucose can be entered in mg/dL or mmol/L; the tool converts.
My HOMA-IR is high — what now?
A high value suggests possible insulin resistance but is not diagnostic; measurement conditions, puberty and clinical context matter. The right step is review with a paediatrician/endocrinologist. Lifestyle (diet, activity, sleep) is often the first step.